2.
Lifestyle - Prescription medications, smoking, alcohol, physical & emotional stressors all impact nutrient status.
For example, NSAIDS (Motrin, Aleve, Advil etc.) can lead to folic acid deficiency (vitamin B9), panthothenic acid (vitamin B5), as well as vitamin C and Iron.
Anti-inflammatories (Prednisone etc.) can lead to deficiencies in vitamin D, vitamin C, vitamin B6, vitamin B12 & vitamin B9 (folic acid)